40. Yu, Y.-Z.#; Li, J.-T.#; Yin, Y.-Q.; Zhuo, C.-X.* Asymmetric deoxygenative difunctionalization of 1,2-dicarbonyl compounds enabled by phosphinite and chiral salen-molybdenum catalyst synergy. Angew. Chem. Int. Ed. 2026, e2472486. (# Equal contribution)
39. Shi, X.-N.#; Wang, J.-L.#; Chen, Z.#; Wang, D.-K.#; Wu, G.-Y.; Peng, J.-M.; Qi, X.*; Zhuo, C.-X.* Vicinal dicarbonyl reprogramming via molybdenum-catalyzed formal C(O)−C(O) bond cleavage. J. Am. Chem. Soc. 2026, 148, 11274–11283. (# Equal contribution)
38. Yu, Y.-Z.; Fang, G.; Su, H.-Y.; Zhuo, C.-X.* Synthesis of meta-substituted benzenes via Mo-Catalyzed intermolecular deoxygenative coupling of ynones and allylic amines. Org. Synth. 2025, 102, 381−397.
37. Yao, J.-S.#; Su, X. #; Yu, Y.-Z.; Wu, J.-B.; Qu, S.*; Zhuo, C.-X.* Divergent synthesis of 2-quinolinones and indolin-3-ones via Mo-catalyzed controllable carbonyl deoxygenative coupling and formal deoxygenative N—H insertion reactions. Chin. J. Chem. 2025, 43, 1538−1546. (# Equal contribution)
36. Fang, G.#; Yu, Y.-Z.#; Zhuo, C.-X.* Synthesis of 3,5-disubstituted anilines via sequential Mo-catalyzed deoxygenative benzene formation and Pd-catalyzed amination reactions. Synthesis 2025, 57, 1922−1927. (# Equal contribution)
(Invited contribution as a Feature Article)
35. Yu, Y.-Z.; Su, H.-Y.; Zhuo, C.-X.* Anilines formation via molybdenum-catalyzed intermolecular reaction of ynones with allylic amines. Angew. Chem. Int. Ed. 2024, e202412299.
34. Wang, J.-L.#; Li, J.-T.#; Wu, G.-Y.; Zhuo, C.-X.* Recent advances in molybdenum catalyzed asymmetric organic transformations. Trends Chem. 2024, 6, 487−501. (# Equal contribution)
(Invited contribution to the Special issue: Emerging leaders in chemistry)
Highlighted by Meet our emerging leaders in chemistry – part II. Trends Chem. 2024, 6, 409−414.
33. Wang, J.-L.#; Wu, G.-Y. #; Luo, J.-N.; Liu, J.-L.; Zhuo, C.-X.* Catalytic intermolecular deoxygenative coupling of carbonyl compounds with alkynes by a Cp*Mo(II)-catalyst. J. Am. Chem. Soc. 2024, 146, 5605−5613. (# Equal contribution)
32. Li, J.-T.; Fang, G.; Wu, G.-Y.; Zhuo, C.-X.* Modular access to diverse amphoteric α-boryl aldehydes or borylated heterocycles via photoredox catalysis. ACS Catal. 2023, 13, 12648−12655.
31. Dong, Y.-Q.#; Shi, X.-N.#; Cao, L.-Y.#; Bai, J.; Zhuo, C.-X.* Molybdenum-catalyzed carbonyl-carbonyl olefination reaction for heterocycle syntheses. Org. Chem. Front. 2023, 10, 3544−3552. (# Equal contribution)
30. Yu, Y.-Z.; Bai, J.; Peng, J.-M.; Yao, J.-S.; Zhuo, C.-X.* Modular access to meta-substituted benzenes via Mo-catalyzed intermolecular deoxygenative benzene formation. J. Am. Chem. Soc. 2023, 145, 8781−8787. (Selected as JACS Supplementary Cover) (Top 20 most downloaded articles in April 2023)
Highlighted by Org. Process Res. Dev. 2023, 27, 993.
29. Shi, X.-N.; Wang, J.-L.; Wu, J.-B.; Zhuo, C.-X.* Synthesis of 2-boryl allylboronates by a bimetallic platinum/zinc-promoted diborylation of propargylic amines. Synlett 2023, 34, 1573−1574. (Invited contribution to the Special Edition Thieme Chemistry Journals Awardees 2022)
28. Cao, L.-Y.; Wang, J.-L.; Wang, K.; Wu, J.-B.; Wang, D.-K.; Peng, J.-M.; Bai, J.; Zhuo, C.-X.* Catalytic asymmetric deoxygenative cyclopropanation reactions by a chiral salen-Mo catalyst. J. Am. Chem. Soc. 2023, 145, 2765−2772. (Selected as JACS Supplementary Cover)
27. Dong, Y.-Q.#; Wang, K.#; Zhuo, C.-X.* Molybdenum-catalyzed intermolecular deoxygenative cross coupling reactions of 1,2-diketones with ɑ-ketoamides. ACS Catal. 2022, 12, 11428−11435. (# Equal contribution) (Top 20 most downloaded articles in October 2022)
26. Li, J.-T.; Luo, J.-N.; Wang, J.-L.; Wang, D.-K.; Yu, Y.-Z.; Zhuo, C.-X.* Stereoselective intermolecular radical cascade reactions of tryptophans or ɤ-alkenyl-α-amino acids with acrylamides via photoredox catalysis. Nat. Commun. 2022, 13, 1778. DOI: 10.1038/s41467-022-29464-5.
25. Wang, J.-L.; Zhuo, C.-X.* Catalytic deoxygenative cyclopropanation of 1,2-dicarbonyl or monocarbonyl compounds via molybdenum catalysis. Synlett 2022, 33, 599−608. (Invited Synpacts)
24. Cao, L.-Y.; Luo, J.-N.; Yao, J.-S.; Wang, D.-K.; Dong, Y.-Q.; Zheng, C.; Zhuo, C.-X.* Molybdenum-catalyzed deoxygenative cyclopropanation of 1,2-dicarbonyl or mono-carbonyl compounds. Angew. Chem. Int. Ed. 2021, 60, 15254−15259.
Highlighted by Nature Catalysis 2021, 4, 347. & Synfacts 2021, 17, 906.
Before joining Xiamen University:
23. Zhuo, C.-X.; Fürstner, A.* Catalysis-based total syntheses of pateamine A and DMDA-Pat A. J. Am. Chem. Soc. 2018, 140, 10514−10523. (Top 20 most downloaded articles in September 2018)
Highlighted by Synfacts 2018, 14, 1114.
22. Zhuo, C.-X.; Fürstner, A.* Concise synthesis of a pateamine A analogue with in vivo anticancer activity based on an iron catalyzed pyrone ring-opening/cross coupling. Angew. Chem. Int. Ed. 2016, 55, 6051−6056.
21. Zhuo, C.-X.; Zhang, X.; You, S.-L.* Enantioselective synthesis of pyrrole fused piperazine and piperazinone derivatives via Ir-catalyzed asymmetric allylic amination. ACS Catal. 2016, 6, 5307−5310.
Highlighted by Synfacts 2016, 12, 1043.
20. Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.* Enantioselective construction of spiroindolines with three contiguous stereogenic centers and chiral tryptamine derivative via the reactive spiroindolenine intermediates. Angew. Chem. Int. Ed. 2015, 54, 14146−14149.
Highlighted by Synfacts 2016, 12, 151.
19. Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.* Enantioselective synthesis of pyrrole based spiro- and polycyclic derivatives via Ir-catalyzed asymmetric allylic dearomatization and controllable migration reactions. Angew. Chem. Int. Ed. 2015, 54, 8475−8479.
Highlighted by Synfacts 2015, 11, 944.
18. Zhuo, C.-X.; Zhou, Y.; You, S.-L.* Highly regio- and enantioselective synthesis of poly-substituted 2H-pyrroles via Pd-catalyzed intermolecular asymmetric allylic dearomatization of pyrroles. J. Am. Chem. Soc. 2014, 136, 6590−6593.
Highlighted by J. Am. Chem. Soc. Spotlights (J. Am. Chem. Soc. 2014, 136, 6511.)
Highlighted by Synfacts 2014, 10, 820. & Organic Chemistry Portal.
17. Zhuo, C.-X.; Zheng, C.; You, S.-L.* Transition-metal catalyzed asymmetric allylic dearomatization reactions. Acc. Chem. Res. 2014, 47, 2558−2573.
16. Zhuo, C.-X.; You, S.-L.* Palladium-catalyzed intermolecular allylic dearomatization reaction of a-substituted-β-naphthol derivatives: scope and mechanistic investigation. Adv. Synth. Catal. 2014, 356, 2020−2028.
15. Zhuo, C.-X.; You, S.-L.* Palladium-catalyzed intermolecular asymmetric allylic dearomatization reaction of naphthol derivatives. Angew. Chem. Int. Ed. 2013, 52, 10056−10059.
Highlighted by Synfacts 2013, 9, 1308. & Chin. J. Org. Chem. 2013, 33, 2440.
14. Zhuo, C.-X.; Wu, Q.-F; Zhao, Q.; Xu, Q.-L.; You, S.-L.* Enantioselective functionalization of indoles and pyrroles via an in-situ formed spiro-intermediate. J. Am. Chem. Soc. 2013, 135, 8169−8172.
Highlighted by Synfacts 2013, 9, 874.
13. Zhuo, C.-X.; Zhang, W.*; You, S.-L.* Catalytic asymmetric dearomatization reactions. Angew. Chem. Int. Ed. 2012, 51, 12662−12686.
12. Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.* Asymmetric dearomatization of pyrroles via Ir-catalyzed allylic substitution reaction: enantioselective synthesis of spiro-2H-pyrroles. Chem. Sci. 2012, 3, 205−208.
11. Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Mechanistic insights into the Pd-catalyzed intermolecular asymmetric allylic dearomatization of multisubstituted pyrroles: understanding the remarkable regio- and enantioselectivity. J. Am. Chem. Soc. 2014, 136, 16251−16259.
10. Ye, K.-Y.; Cheng, Q.; Zhuo, C.-X.; You, S.-L.* An iridium(I) N-heterocyclic carbene complex catalyzes asymmetric intramolecular allylic amination reactions. Angew. Chem. Int. Ed. 2016, 55, 8113−8116.
9. Wu, Q.-F; Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Highly efficient synthesis and stereoselective migration reactions of chiral five-membered aza-spiroindolenines: scope and mechanistic understanding. Chem. Sci. 2016, 7, 4453−4459.
8. Zhou, Y.; Zhuo, C.-X.; Gu, Q.; You, S.-L.* Intermolecular dearomatization reaction of pyrroles promoted by silica gel. Adv. Synth. Catal. 2015, 357, 912−916 (VIP).
7. Wang, S.-G.; Yin, Q.; Zhuo, C.-X.; You, S.-L.* Asymmetric dearomatization of β-naphthols through an amination reaction catalyzed by a chiral phosphoric acid. Angew. Chem. Int. Ed. 2015, 54, 647−650.
6. Yang, Z.-P.; Zhuo, C.-X.; You, S.-L.* Ruthenium-catalyzed intramolecular allylic dearomatization/migration reaction of indoles and pyrroles. Adv. Synth. Catal. 2014, 356, 1731−1734.
5. Zhao, Q.; Zhuo, C.-X.; You, S.-L.* Enantioselective synthesis of N-allylindoles via palladium-catalyzed allylic amination/oxidation of indolines. RSC Adv. 2014, 4, 10875−10878.
4. Xu, Q.-L.; Zhuo, C.-X.; You, S.-L.* Highly enantioselective synthesis of tetrahydrocarbolines via iridium-catalyzed intramolecular Friedel-Crafts type allylic alkylation reactions. Org. Lett. 2013, 15, 5909−5911.
3. Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Ir-catalyzed allylic alkylation reaction with N-aryl phosphoramidite ligands: scope and mechanistic studies. J. Am. Chem. Soc. 2012, 134, 4812−4821.
2. Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.* Iridium-catalyzed intramolecular asymmetric allylic dearomatization of phenols. Angew. Chem. Int. Ed. 2011, 50, 4455−4458.
1. Xia, J.-B.; Zhuo, C.-X.; You, S.-L.* Synthesis of Cyclopropane-containing Building Blocks via Ir-Catalyzed Enantioselective Allylic Substitution Reaction. Chin. J. Chem. 2010, 28, 1525−1528.
